Type III secretion-dependent hemolytic activity of enteropathogenic Escherichia coli.

نویسندگان

  • J Warawa
  • B B Finlay
  • B Kenny
چکیده

Enteropathogenic Escherichia coli (EPEC) was found to exhibit a type III secretion-dependent, contact-mediated, hemolytic activity requiring the EspA, EspB, and EspD secreted proteins. EspB and EspD display homology to pore-forming molecules. Our data suggest a mechanism to explain the requirement for all three Esp proteins in the transfer of EPEC proteins, such as Tir, into target cells.

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عنوان ژورنال:
  • Infection and immunity

دوره 67 10  شماره 

صفحات  -

تاریخ انتشار 1999